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24-Jun-2020 04:26

Wiley also publishes its books in a variety of electronic formats. Even persons from seemingly disparate occupations, such AN OVERVIEW OF THE DRUG DISCOVERY AND DEVELOPMENT PROCESS 3 Figure 1.1 The stages from drug discovery to marketing approval.

From discovery to marketing approval of a drug, the stages involved are shown in Fig. Drug Discovery: This process involves finding the target that causes or leads to the disease.Personnel with different disciplines and expertise are needed to discover and develop drugs targeting diseases at the cellular and molecular levels.It is estimated that, on average, a drug takes 10–12 years from initial research to reach the commercialization stage.The development work has to follow Good Laboratory Practice (GLP) to ensure that proper quality system and ethical considerations are established.

Only compounds that satisfy certain performance and safety criteria will proceed to the next stage of clinical trial.Next, chemical or biological compounds are screened using specific assays and are tested against these targets to find leading drug candidates for further development.